The core objective of this project is to improve care of children with traumatic brain injury and concern for abuse by using machine learning to recognize new patterns of brain injury that are associated with abuse and with poor outcomes. The team has developed cutting-edge MRI-based imaging methods, and are well-suited to identify new patterns […]
The team has begun enrolling participants in a randomized clinical trial investigating the effect of early sub-symptom aerobic exercise on psychosocial outcomes, and monitoring participants for the subsequent two months. Data thus far indicates a beneficial effect of early exercise on persistent post-concussion symptoms and anxiety, relative to standard-of-care. However, these data are preliminary and […]
This project aims to explore impact of acute mTBI on the human microbiome and the effects of the human microbiome on mental health outcomes post-injury. Since the start of this longitudinal study, regulatory approval has been obtained and study personnel were hired and trained. Nine participants have been recruited. Initial samples at baseline were obtained […]
The effects of traumatic brain injury persist far longer than just the acute, post-injury period. Individuals suffering TBI often complain of disrupted sleep, which effects cognitive performance and mood, among other symptoms. These symptoms may persist for years or decades. This project tests the hypothesis that replacement of a key brain chemical will alleviate post-TBI […]